Search results for "Skin rheology"

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COMBINATION OF ARGAN OIL AND PHOSPHOLIPIDS FOR THE DEVELOPMENT OF AN EFFECTIVE LIPOSOME-LIKE FORMULATION ABLE TO IMPROVE SKIN HYDRATION AND ALLANTOIN…

2016

Allantoin is traditionally employed in the treatment of skin ulcers and hypertrophic scars. In the present work, to improve its local deposition in the skin and deeper tissues, allantoin was incorporated in conventional liposomes and in new argan oil enriched liposomes. In both cases, obtained vesicles were unilamellar, as confirmed by cryo-TEM observation, but the addition of argan oil allowed a slight increase of the mean diameter (∼130nm versus ∼85nm). The formulations, especially those containing argan oil, favoured the allantoin accumulation in the skin, in particular in the dermis (∼8.7μg/cm(2)), and its permeation through the skin (∼33μg/cm(2)). The performances of vesicles as skin d…

3003Pig skinfood.ingredientSwineChemistry PharmaceuticalSkin AbsorptionPharmaceutical ScienceArgan oil02 engineering and technologyAdministration Cutaneous030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compoundDrug Delivery Systems0302 clinical medicineAllantoinfoodDermisElastic ModulusSkin rheologymedicineAnimalsPlant OilsAllantoinSofteningPhospholipidsSkinDrug CarriersLiposomeChromatographyintegumentary systemChemistryVesicleLiposomes; Argan oil; Phospholipids; Pig skin; Turbiscan lab; Skin rheology; Skin hydrationPermeation021001 nanoscience & nanotechnologyTurbiscan labmedicine.anatomical_structureSkin hydrationArgan oilLiposomesDermatologic Agents0210 nano-technologyDrug carrierargan oil; liposomes; phospholipids; pig skin; skin hydration; skin rheology; turbiscan lab; 3003
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